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Research Related Medical Articles on Papillon

This page carries articles and presentations providing medical background
to Papillon Contact X-Ray Brachytherapy 

(Clicking on a title will open the article  - Adobe or other pdf reader may be required)

Zurich Presenttaion 2024
Watch & Wait – Management of special situations and recurrences.


The safety and efficacy of total mesorectal excision (TME) surgery following dose-escalation: Surgical outcomes from the organ preservation in early rectal adenocarcinoma (OPERA) trial, 



New hope from OPERA trial for surgically fit rectal cancer patients who wish to have organ preservation.

Colorectal Disease. 2022;00:1–2.

Bringing organ preservation closer for selected patients with rectal cancer.

Lancet Gastroenterol Hepatol 2023 Published Online February 16, 2023

Neoadjuvant chemoradiotherapy with radiation dose escalation with contact x-ray brachytherapy boost or external beam radiotherapy boost for organ preservation in early cT2–cT3 rectal adenocarcinoma (OPERA): a phase 3, randomised controlled trial. Published online February 16, 2023


The Role of Contact X-Ray Brachytherapy in Early Rectal Cancer - Who, when and How?

Sun Myint A et al., The Role of Contact X-Ray Brachytherapy in Early Rectal Cancer e Who, when and How? Clinical Oncology,



A multi-centre analysis of adjuvant contact X-ray brachytherapy (CXB)in rectal cancer patients treated with local excision – Preliminary results of the CONTEM1 study. 

                                                            A. Dhadda, Radiotherapy and Oncology 162 pp (2021) 195–201


Beneficiaries of radical surgery among complete responders to neoadjuvant chemoradiotherapy in rectal cancer.                                                     Shu Zhang, et., al. (2021)  Cancer Science : Wiley Library


Patient information and timing prior to consent for Contact X-Ray Brachytherapy (Papillon): Are we doing the process right?                      A. Sun Myint  et., al. (2019) EC Gastroenterology & digestive system  Research Article


Role of radiotherapy in the treatment of rectal cancer in older patients.
                                               A. Sun Myint, & J.P. Gerard, (2020)  European Journal of Surgical Oncology

Patient Choice in NHS : capturing "decision regret".

                                               A. Sun Myint (2019) British Medical Journal ;366:I5363 doi: 10.1136bmj   


Treatment: the role of contact X-ray brachytherapy (Papillon) in the management of early rectal cancer.

                                               A. Sun Myint et,. al. (2019) Colorectal Disease : The Association of Coloproctology                                                      of Great Britain and Ireland

Contact X-ray Brachytherapy as an Adjunct to a Watch and Wait Approach is an Affordable Alternative to Standard Surgical Management of Rectal Cancer for Patients with a Partial Clinical Response to Chemoradiotherapy

                                                  C. Rao, (2018) Clinical Oncology  

Low-energy  contact X-Ray brachytherapy (the Papillon techniques) for early-stage rectal cancer.                                                                                NICE Interventional Procedure Guidance (2015)

Contact radiotherapy for elderly patients with early low cancers. 

                                                      A. Sun Myint (2013):  British Journal of Hospital Medicine

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